Disruption Mission Guide

The endless mission type ‘Disruption’ was introduced during Update 25 and not only brought some fresh, new content into Warframe, but also set the foundation for even more content: Update 25.7 expanded the amount of missions from just one (on Jupiter) with six new Disruption missions all over the star system.

While it is often compared to Mobile Defense missions, Disruption features an unique play style and brings its own expectations, specifications and problems.

Luckily, we are here to help you out with everything you need to know and will tell you exactly how it works, what equipment you should think about bringing into the missions and you will also find some tips and tricks about the game mode. So keep on reading!

Basic Information

Once you’ve loaded into a Disruption mission you need to find the marked console and activate it, which will then start the endless mission.

If you rather wait for your team to fully load up, wait with activating it – otherwise go ahead. Once you’ve activated the console, you will be able to see four conduits on your HUD and mini map, which are colored in blue, cyan, white and red.

At the same time, enemies will start spawning on the map: You will get the normal enemy spawns, determined by the fraction of the map (Grineer, Corpus or Infested), but you also get Amalgam spawns.

Killing the latter will drop one colored key, which needs to be picked up and carried to the proper conduit (so the red key goes to the red conduit, etc.).

After you activated the conduit with the key, a timer will start and a Demolyst will spawn somewhere on the map.

The Demolysts are basically very tough Amalgams and only have one goal: Run towards the activated conduit and blow themselves up, destroying the conduit in the process.

Your job is to kill it before that happens. They do emit a beeping sound, so you will be able to hear them long before you see them. Run in their direction and kill them as fast as possible.

Once you’ve killed the Demolyst, the conduit is save and solved for the round and you only need to repeat this process with the other three conduit to finish your current round.

You can then either extract or stay in the mission to get fight more rounds and get better rewards.

If you lose all conduits in one round, the mission will be failed, but as long as at least one conduit survives you will be able to start a new round.

Disruption Tips and Tricks

Even though the mode is fairly straight forward, there are some tips and tricks to follow.

Here are a quick ideas you should keep in the back of your mind and follow as needed:

Spare keys

Sometimes you get a second key drop for the same color (e.g. two red conduit keys). These keys will vanish after the round ends – unless you carry it in your hands. That way you can bring one key into the next round and speed up the whole round.

Magus Lockdown

The Arcane (bought from Little Duck on Fortuna) for your operator will drop a Tether Mine right under you after you performed a Void Dash and traps enemies in range for four seconds. That way you can easily hold a Demolyst and kill it before it reaches the conduit.

Activate multiple conduits

You don’t have to do one conduit after another. If you have a good enough team you can activate them as you please and reduce the round time by a lot.

Just make sure that the Demolysts die fast enough before blowing up.

Spread out

If everyone in your team is able to kill a Demolyst within a few seconds, spreading out on the map can reduce the time as well.

Demolysts usually spawn far away from the conduit they’re trying to blow up, so spreading out will make sure you’ll find it (and kill it) in a short amount of time.

Use colored keys on the porper colored conduit.

Conduit Effects

The second you activate a conduit (using the right key) it will display either a buff or debuff. If you lose the conduit due to a Demolyst exploding and it had a debuff displayed, said debuff will persist until the end of the round.

If you kill the Demolyst in time and the conduit had a buff displayed, you will keep the buff until the end of the round. Here are all buffs and debuffs you might come across:

Buffs Debuffs
Resource Boost +50% Energy Drain Mode
Credits Boost +50% Shield Drain Mode
Fire Rate Boost Health Drain Mode
Speed Boost Enemy Damage Boost
Tenno Lifesteal Enemy Speed Enhancement
Conduit Resupply (drops health, ammo and energy around conduits) Enemy Elemental Weapons

Enemy Ability Resistance

Enemy Damage Resistance

System Overload (Conduits are electrified)

Eximus Wave

Stronger Amalgams

Minefield (Mines spawn around the conduits)

Disruption Locations

There are currently seven different locations for Disruption missions and even though the mechanics are the same on every Disruption mission, you’re going to see differences between the different nodes.

First and foremost there are missions for each of the three factions (Grineer, Corpus and Infested), but they also differ in enemy level and mainly in the drops you can get there.

So even if you manage to farm one of these missions for every drop, you probably will have to farm at least some of the other Disruption locations as well.

Here are all the Disruption locations:

Planet Node Name Level Faction
Mars Olympus 15 – 20 Grineer
Jupiter Ganymede 35 – 40 Corpus
Neptune Laomedeia 25 – 30 Corpus
Kuva Fortress Tamu 35 – 40 Grineer
Sedna Kelpie 35 – 40 Grineer
Uranus Ur (Dark Sector) 30 – 35 Infestation
Lua Apollo 35 – 40 Corpus

Special Disruption Reward System

It is also important to mention that Disruption doesn’t follow the standard AABC rotation system that most endless missions in Warframe use.

Instead you need to have an eye on your performance (the more conduits survive the better) and the round progression (later rounds have better drops).

It works somewhat similar to the Arbitrations mode, where you always get the higher tier rewards once you’ve reached a certain number of rounds.

The following schema sums up how the rewards are distributed:

Round 1 conduit survived 2 conduits survived 3 conduits survived 4 conduits survived
1 Tier A Tier A Tier A Tier B
2 Tier A Tier A Tier B Tier B
3 Tier A Tier B Tier B Tier C
4+ Tier B Tier B Tier C Tier C

So what that basically means is that once you’ve reached round 4, you will always get a C drop as long as at least three conduits survived.

If you are trying to farm for the Tier C reward (and you will do that), staying for a longer time is the best way to do that. It also means that you get your first drop chance for Tier C after three rounds instead of four!

Disruption offers a lot of different (special) rewards.

Special Disruption Mode Rewards

We’re not going to show you the full drop table for all seven Disruption nodes, because you can easily find them at the official Drop Table or find them in the Wiki.

Instead we’re going to talk about the special rewards you’re going to farm Disruption for:

Gauss Blueprints

This is probably the main reason a lot of players are going to farm Disruption.

Tier C on Kelpie (Sedna) has a 10% chance (each) to drop the Gauss Chassis Blueprint, the Gauss Neuroptics Blueprint or the Gauss Systems Blueprint.

So keep on grinding the mission until you finally have all the blueprints needed.

Universal Medallions

They basically work the same way as the syndicate seeds (you might find these in syndicate missions) do, but they are without an affiliation to an syndicate.

They also can be used after you already maxed out your daily standing and still increase your standing with one of the six main syndicates (New Loka, The Perrin Sequence, Red Veil, Arbiter of Hexis, Cephalon Suda, Steel Meridian).

They are a reward from the Tier C pool and have a ~5% chance to be rewarded on every Disruption node (with the exception of Olympus, Mars).

Acceltra and Akarius

Gauss’s signature weapons aren’t a reward for finishing Disruption rounds, but rather drop from killed Demolysts on the Dark Sector node Ur (Uranus).

With a fairly low drop chance (1,25% for each the Acceltra and the Akarius) you probably have to run the mission a couple of times.

Lua Lens Blueprint

The newest lens converts 3,25% of Affinity into Focus – which means the Lua Lens is ~44% better than the already great Eidolon Lens.

With a drop chance of 10,1% on Tier C on Appolo (Lua) it is also not unlikely to farm a couple of them in a fair amount of time.


If you’re running Tamu (Kuva Fortress) Disruption you will get 100 Kuva for Tier A, 200 Kuva for Tier B and 350 Kuva for Tier C, with a 5% chance to get one Universal Medallion on Tier C instead.

The Best Weapons and Warframes

While there are a wide range of Warframes you could successfully play in Disruption, you really need a good way to kill the Demolysts as fast as possible.

Bringing a strong shotgun (e.g. the Vaykor Hek or the Boar Prime) or the current meta pick for secondaries – the Catchmoon – is usually more than enough.

High critical damage rifles like the Soma Prime or the Boltor Prime are also great picks.

You could even try and play a high damage sniper. In the end you really just need a weapon with enough damage output to burst down the Demolyst in a few seconds, so play what you like most (as long as it can kill stuff fast enough).

There are also a few good Warframes that will make the whole mission pretty easy. Here are our favorite picks:

  • Wukong: Having a good Primal Wukong Build is actually a great way to play Disruption. The melee build can usually kill the Demolysts within a few hits and since Wukong is pretty tanky and has his clone for better damage output you will be able to stay until you have everything you want and need.
  • Mesa: Playing with the gunslinger sometimes feels like cheating. The auto-aim is great on Disruption nodes with big rooms and since your ‘Peacemaker’ ability can also hit Demolysts, you can kill them within a second or two.
  • Wisp: Playing a support is often underrated, but Wisp is just the right amount of support and semi-DPS. Place your motes strategically and your team can easily carry you through long runs. Also, the crowd control of your Shock Mote is very strong.
  • Khora: Even though only Demolysts can kill the conduits, you sometimes want a little bit of space to play with. Khora’s Strangledome will offer exactly that protection and also give you enough energy and health drops to survive without any trouble.
  • Area-of-Effect Warframes: Saryn, Equinox or Volt are a great way to kill everything but the Demolysts and sometimes you can even use your abilities against Amalgams or Demolysts.
  • Crowd control: If you’re having trouble surviving in longer runs (or even in shorter runs), bringing a Slow Nova, a Crowd Control Nyx or even a Vauban can be a great way to improve your survivability. Most crowd control abilities also affect the Demolysts, which makes killing them in time even more easy.
Make sure to kill the Demolysts before they explode and destroy conduits.


With the release of Update 25.7.0 and the introduction of six new Disruption nodes, the mode actually became very interesting and fun-to-play.

Just make sure you understand the basic mechanics, bring a good enough loadout to stay for a couple of Tier C rewards and don’t forget to enjoy grinding through Warframe.

If you have some great ideas to add or if we missed some important information, feel free to leave us a comment and help out the community!

5 thoughts on “Disruption Mission Guide”

  1. The system overload is incorrect. It gives the description for electrified conduits. I am pretty sure System overload can only activate on Jupiter nodes and it activates all traps on the mission. Gas traps, electriticy sentries, distressed pipes, etc.

  2. Baruuk can cause the Demolysts to completely stop in their tracks and give you quite a bit more time to kill them.

    • I remember it being on Kelpie a few years back as well. Some mission types have been moved around in last few patches, Sedna disruption is one of them.


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